Description: HumanPAK1kinase(UniProt:Q13153;NCBI:NM_002576)belongstoafamilyofp21-activatedkinases.Theseserine/threoninekinasesserveastargetsforthesmallGTPbindingproteinsCdc42andRacandhavebeenimplicatedinawiderangeofBIOLOGicalactivities.PAK1kinaseregulatescellmotilityandmorphology.PAK1KDisarecombinantwildtypehumanPAK1kinasedomain(aminoacids248–545offull-lengthhumanPAK1)expressedinE.coliandpurifiedtonearhomogeneity.PAK1KDdoesnothavetheinhibitoryswitchdomainandhashighspecificactivity. MolecularMassandPhosphorylation: Thecalculatedmassis33,646.PAK1KDisfullyphosphorylatedatT423andpartiallyphosphorylatedatadditionalsiteswithmeasuredmassof33,728(1P),33,808(2P),33,889(3P),and33,968(4P). StABIlityandStorage: Stableat-70oCfor12monthsfromdateofreceipt.Proteinshouldbethawedonice.Proteincanbeflash-frozeninliquidnitrogenandstoredat-70oC. Applications: Enzymaticstudies,inhibitorscreen,andselectivityprofiling Highconcentrationavailableforcrystallization |
Accelagen常用产品报价单
产品名 | 货号 | 公司分类 | 商城分类 | 美金价 |
Accelagen/TurboLigation Kit/L0110S/ 100 reactions | L0110S | Enzyme Toolbox | 蛋白酶类 | 546.00 | Accelagen/PAK1KD (recombinant human PAK1 kinase domain)/K0104S/ 10 µg | K0104S | Kinases | 激酶 | 360.00 |