Description: HumanPAK2kinase(UniProt:Q13177;NCBI:NM_002577)belongstoafamilyofp21-activatedkinases.Theseserine/threoninekinasesareregulatedbythesmallGTPbindingproteinsCdc42andRacandhavebeenimplicatedinawiderangeofBIOLOGicalactivities.PAK2isactivatedbyproteolyticcleavageduringcaspase-mediatedapoptosis,andmayplayaroleinregulatingtheapoptoticeventsinthedyingcell. PAK2KDisarecombinantwildtypehumanPAK2kinasedomain(aminoacids227–524offull-lengthhumanPAK2)expressedinE.coliandpurifiedtonearhomogeneitywithhighspecificactivity. 品牌介绍
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