Description: HumanPAK3kinase(UniProt:O75914;NCBI:NM_001128166)belongstoafamilyofp21-activatedkinases.Theseserine/threoninekinasesserveastargetsforthesmallGTPbindingproteinsCdc42andRacandhavebeenimplicatedinawiderangeofBIOLOGicalactivities.OverexpressionofPAK3hasbeendetectedincertaintypesofcancer.MutationsofPAK3havebeenassociatedwithlearningdisABIlityandX-linkedmentalretardation.PAK3KDisarecombinantwildtypehumanPAK3kinasedomain(aminoacids246-544offull-lengthhumanPAK3)expressedinE.coliandpurifiedtonearhomogeneity. MolecularMassandPhosphorylation: Thecalculatedmassis33,758.PAK3KDisphosphorylatedonT421andpartiallyphosphorylatedatadditionalsiteswithmassmeasuredat33,835(1P),33,915(2P),33,995(3P). StabilityandStorage: Stableat-70oCfor12monthsfromdateofreceipt.Proteinshouldbethawedonice.Proteincanbeflash-frozeninliquidnitrogenandstoredat-70oC. Applications: Enzymaticstudies,inhibitorscreen,andselectivityprofiling Highconcentrationavailableforcrystallization |
Accelagen常用产品报价单
产品名 | 货号 | 公司分类 | 商城分类 | 美金价 |
Accelagen/TurboLigation Kit/L0110S/ 100 reactions | L0110S | Enzyme Toolbox | 蛋白酶类 | 546.00 | Accelagen/PAK1KD (recombinant human PAK1 kinase domain)/K0104S/ 10 µg | K0104S | Kinases | 激酶 | 360.00 |